Motif ID: MEF2{A,B,C,D}.p2

Z-value: 2.839


Transcription factors associated with MEF2{A,B,C,D}.p2:

Gene SymbolEntrez IDGene Name
MEF2A 4205 myocyte enhancer factor 2A
MEF2B 100271849 myocyte enhancer factor 2B
MEF2BNB-MEF2B 4207 MEF2BNB-MEF2B readthrough
MEF2C 4208 myocyte enhancer factor 2C
MEF2D 4209 myocyte enhancer factor 2D

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MEF2Cchr5_-_882356240.775.0e-04Click!
LOC729991-MEF2Bchr19_-_19164222-0.533.4e-02Click!
MEF2Achr15_+_979907050.448.9e-02Click!
MEF2Dchr1_-_1547371300.312.5e-01Click!
MEF2Bchr19_-_19142090-0.194.9e-01Click!


Activity profile for motif MEF2{A,B,C,D}.p2.

activity profile for motif MEF2{A,B,C,D}.p2


Sorted Z-values histogram for motif MEF2{A,B,C,D}.p2

Sorted Z-values for motif MEF2{A,B,C,D}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MEF2{A,B,C,D}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_111119846 8.437 NM_001142483
 C5orf13
chromosome 5 open reading frame 13
chr12_+_79625538 7.589 NM_002469
 MYF6
myogenic factor 6 (herculin)
chr10_+_69539255 7.498 NM_032578
 MYPN
myopalladin
chr4_+_169654742 6.542 NM_001166108
NM_016081
 PALLD

palladin, cytoskeletal associated protein

chr5_+_155686333 6.418 NM_000337
NM_001128209
NM_172244
 SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr10_-_75085754 6.003 NM_001114133
 SYNPO2L
synaptopodin 2-like
chrX_-_21686079 5.810 NM_014332
 SMPX
small muscle protein, X-linked
chr2_+_88148413 5.539 NM_198274
 SMYD1
SET and MYND domain containing 1
chr10_-_75080784 4.893 NM_024875
 SYNPO2L
synaptopodin 2-like
chr2_+_170074457 4.863 NM_006063
 KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr8_+_67201684 4.834 NM_033058
NM_184085
NM_184086
NM_184087
 TRIM55



tripartite motif containing 55



chr7_-_41709191 4.650 NM_002192
 INHBA
inhibin, beta A
chr15_-_68781662 4.616 NM_001008224
 UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr10_+_50177192 4.276 NM_001135196
NM_199459
 C10orf71

chromosome 10 open reading frame 71

chr2_-_190635566 4.233 NM_005259
 MSTN
myostatin
chr5_+_53787187 4.219 NM_006308
 HSPB3
heat shock 27kDa protein 3
chr16_+_31132842 4.187 NM_001008274
 TRIM72
tripartite motif containing 72
chr7_+_93862137 3.922 COL1A2
PLAG1
collagen, type I, alpha 2
pleiomorphic adenoma gene 1
chr6_-_139654807 3.832 NM_153235
 TXLNB
taxilin beta
chr3_-_39209075 3.797 NM_194293
NM_001198621
 XIRP1

xin actin-binding repeat containing 1


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
4.61 3.32e-02 GO:0006941 striated muscle contraction
4.61 3.32e-02 GO:0030049 muscle filament sliding
4.61 3.32e-02 GO:0033275 actin-myosin filament sliding
4.49 4.40e-02 GO:0070252 actin-mediated cell contraction
3.07 9.24e-06 GO:0003012 muscle system process
2.95 1.57e-05 GO:0007517 muscle organ development
2.75 2.27e-03 GO:0006936 muscle contraction
2.71 4.12e-02 GO:0042692 muscle cell differentiation
2.70 2.40e-06 GO:0061061 muscle structure development

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
7.16 2.92e-02 GO:0031672 A band
6.04 2.74e-02 GO:0032982 myosin filament
5.72 1.59e-05 GO:0030018 Z disc
5.50 1.16e-06 GO:0031674 I band
5.07 2.01e-12 GO:0030017 sarcomere
4.95 3.59e-14 GO:0030016 myofibril
4.95 9.76e-14 GO:0044449 contractile fiber part
4.80 4.61e-14 GO:0043292 contractile fiber

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
3.97 3.49e-02 GO:0008307 structural constituent of muscle